Thymosin Beta-4 fragment studied in preclinical models for its role in cell migration via G-actin sequestration and actin polymerization. >99% pure TB-500 peptide, third-party tested with independent COA on every batch. Fast domestic USA shipping, discreet packaging, no customs delays.
Formula: C₃₈H₆₈N₁₀O₁₄
Molecular Weight: ~888.0 Da
For in-vitro laboratory research use only.
Original price was: $93.98.$89.99Current price is: $89.99.
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TB-500 is a synthetic research peptide derived from Thymosin Beta-4, studied in laboratory settings for its role in cell migration, actin-binding dynamics, and tissue signaling pathways. Every batch of TB-500 peptide sold by Excalibur Peptides is independently lab-tested for purity and identity, with a Certificate of Analysis available for verification. Strictly for research use only — not for human or veterinary use.
TB-500 — Research Overview
TB-500 is a synthetic peptide fragment derived from Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid protein found in virtually all human and animal cells. This TB-500 fragment corresponds to the actin-binding domain of Tβ4 and has been the subject of significant preclinical research interest for its role in cellular repair, migration, and angiogenesis pathways. Excalibur Peptides supplies TB-500 strictly for in vitro and preclinical laboratory research.
What Is TB-500 Peptide?
TB-500 is the synthetic analogue of the active region of Thymosin Beta-4. While the full Tβ4 protein is involved in broader cytoskeletal organization, the TB-500 fragment retains the actin-binding and cell-motility-promoting properties researchers most often study.
| Specification | Detail |
|---|---|
| Common name | TB-500 |
| Source protein | Thymosin Beta-4 (Tβ4) |
| Sequence | Ac-LKKTETQ |
| Molecular formula | C₃₈H₆₈N₁₀O₁₄ |
| Molecular weight | ~888.0 Da |
| Purity | ≥99% (HPLC-verified) |
| Form | Lyophilized powder |
(CAS number intentionally omitted until verified — see note above)
TB-500 Research Applications
Tissue Repair and Wound Healing Models
TB-500 has been extensively studied in preclinical models for its potential role in supporting tissue repair processes, including research on dermal wound closure, muscle fiber regeneration, and tendon/ligament healing models.
Angiogenesis Research
Thymosin Beta-4 and its fragments have been researched in the context of new blood vessel formation, with laboratory studies examining TB-500 in ischemia models, cardiac tissue recovery, and vascular repair research.
Inflammatory Pathway Research
Preclinical research has investigated TB-500’s interactions with inflammatory mediators, particularly within musculoskeletal injury models.
Neurological Research
Emerging preclinical literature has examined TB-500 fragment activity in neuronal repair research, including spinal cord injury and stroke recovery models.
Hair Follicle Research
TB-500 has been studied in hair follicle activation research, with findings suggesting interactions with stem-cell compartments involved in the follicle cycle.
Certificate of Analysis
Every batch of TB-500 sold by Excalibur Peptides is tested by an independent third-party laboratory to verify purity and identity. [View this batch’s COA →]
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